News

Demands of the pharmaceutical sector
The advent of Pharma 4.0 is driving the creation of interconnected factories that can bring drug manufacturing to the next level, boosting productivity and end product quality. To succeed in this digital transformation, pharmaceutical companies need regulatory-compliant, fully integrated automation systems that connect different parts of the plant and monitor all processes. The right system integrator can enhance the reliability, responsiveness and overall performance of the system, supporting manufacturers in the creation of highly effective plants.

Optimal at leading PAT event
The 17th edition of the annual International Forum on Process Analytical Chemistry (IFPAC) was a great success for event sponsor Optimal Industrial Technologies. During this year’s digital event, the company welcomed high attendance and positive feedback to its presentation ‘Implementation of PAT and Data Systems to Enhance Quality, Cost and Manufacturing Time’. The company showcased how its software, synTQ, can enhance quality assurance strategies while reducing manufacturing times and costs in a regulatory compliant way.

Optimal Industrial Technologies expands
Increasingly, manufacturers from different sectors are turning to Optimal Industrial Technologies to improve their product quality and increase output using their existing manufacturing infrastructure. To support this growing demand, the company has moved into a modern facility in Emersons Green, Bristol which has enabled it to expand its operations.

synTQ CFC Summit
Optimal Industrial Technologies will sponsor and exhibit at the inaugural Commercializing Flow Chemistry (CFC) Summit. With flow chemistry quickly gaining momentum, the CFC digital event offers a forum for developers and producers of small molecule drug substances and products to discuss the advantages of adopting this strategy. From the 26th-27th August, attendees will be able to learn how Optimal's Process Analytical Technology (PAT) solution, synTQ, can help companies move from batch to continuous flow chemistry.

PAT medical plastics
Growing ecological awareness and stricter environmental regulations are driving positive changes towards greener, more sustainable practices when it comes to manufacturing with plastics. Process Analytical Technology (PAT) offers a key tool to keep up with these trends and realise even the most ambitious green manufacturing initiatives.

Transforming performance
An ever-increasing number of businesses, particularly in the OSD sector are boosting their competitiveness by shifting toward continuous processing techniques. In this context, is it possible for manufacturers and processors that are not yet ready for continuous or cannot move away from batch-based approaches to thrive?

Leading PAT platform

Optimal Industrial Technologies will be a co-host sponsor and presenter at Proventa International’s online Biomanufacturing & Cell and Gene Therapy Strategy Meeting.



Quality assurance rate
The leak detection rate for in-line pharmaceutical gas analysis during inhaler production has increased by 30 times following the introduction of a new automated quality control solution. The robotised system for Metered Dose Inhaler (MDI) manufacture built by Optimal Industrial Automation means significantly reduced cost and wastage in quality control for MDI manufacture.

Meeting global demand
Today's global public health situation is putting pharmaceutical businesses under enormous pressure to deliver innovative and existing tests and treatments as quickly as possible. Optimal’s comprehensive capabilities in Process Analytical Technology (PAT) and factory automation can support pharmaceutical manufacturers to shorten scale-up times dramatically and increase productivity without expanding their facilities.

What is PAT?
Process Analytical Technology (PAT) is a powerful quality assurance tool that can revolutionise the productivity of automated process manufacturing facilities. However, what is the reality behind the buzzword, and where should prospective users start when implementing PAT?

Virtual access
Optimal Industrial Technologies launches a virtual exhibition stand with an ultra-low environmental impact and zero health risks

The digital twin is here
The global importance of plastic-based medical and drug delivery devices is increasing the business opportunities for those in the medical plastics market. The opportunities to improve competitiveness offered by the fourth industrial revolution (Industry 4.0) will help those medical plastic manufacturers that recognise and adopt them. One of the key emerging Industry 4.0 technologies, the digital twin, has the potential to drive dramatic increases in-process responsiveness, productivity and efficiency.

Deep learning for quality control
Deep learning has the potential to revolutionise a broad range of industries by offering increasingly accurate predictive capabilities with little to no human supervision. These can have a tremendous impact on the manufacturing sector by supporting the application of process analytical technology (PAT) and its concomitant increase in process performance and product quality.

PAT knowledge management optimises SMART Factories
Creating a SMART Factory has the potential to bring huge competitive benefits when utilising big data to improve process efficiency and product quality automatically. While highly desirable from a commercial point of view it does present several challenges, one of which is now being solved with very ‘smart’ process management software.

Process control - CPhI India
Optimal Industrial Technologies reported a highly successful debut at CPhI & P-MEC India 2019. Taking a prominent position on Ambetronic’s booth was the company’s Process Analytical Technology (PAT) knowledge management platform, synTQ, used to boost productivity and cost-efficiency whilst ensuring improved quality, full traceability and data integrity

PAT puts tablet manufacturers on solid ground
Oral solid dosage (OSD) is still the most popular form of drug administration, and as a result, OSD manufacturers are required to meet high demand. To stay ahead of the competition, they need to produce tablets, capsules and sachets on a large scale and in a cost-effective manner - whilst maintaining consistently high product quality standards. A key solution to address these challenges lies in data-driven process analytical technologies (PAT)

QbD & PAT for dummies
Optimal Industrial Technologies, one of the key industry players in process analytical technology (PAT) for industrial processes, has announced the publishing and immediate availability of its free book ‘QbD & PAT for dummies’ which is part of the “dummies” range of books published by Wiley. This provides a starting point for processing and manufacturing industry engineers, designers and integrators seeking to boost productivity and product quality by implementing a PAT strategy.

IFPAC Puerto Rico 2019
At the IFPAC Summer Summit 2019 in Puerto Rico, Optimal Industrial Technologies will showcase synTQ V5 software - a potential cornerstone for building a solid process analytical technology (PAT) framework that addresses the growing need for data-driven smart manufacturing.

2019 USA synTQ User Group Meeting
Optimal Industrial Technologies has announced the next group meeting for users of its market leading Process Analytical Technology (PAT) knowledge management software, synTQ. The two-day event will take place at Normandy Farm, Philadelphia, U.S.A, and will be followed by a two-day synTQ training course at the same venue.

PAT minimises regulatory concerns
Three-dimensional (3D) printing is revealing its potential in the pharmaceutical industry as it turns personalised medicine into reality. In fact, additive manufacturing has the unique ability to deliver quickly, flexibly and economically set amounts of patient-specific drugs with bespoke properties, such as formulations, dosages or geometries. To achieve that and meet strict regulatory requirements, the pharmaceutical industry needs to set-up solid Quality by Design (QbD) strategies and process analytical technologies (PAT).

CPAC Rome Workshop 2019
Optimal Industrial Technologies will sponsor and present at the Center for Process Analysis and Control (CPAC) Rome Workshop 2019. The management and applications team will also discuss how its process analytical technology (PAT) knowledge management platform, synTQ, can support the development and manufacture of innovative sustainable materials, as well as back the shift towards continuous processing.

Industry 4.0 at IFPAC
At IFPAC Washington 2019, Optimal Industrial Technologies will showcase (stand 308) the latest developments for its PAT knowledge management platform synTQ, while also delivering two significant presentations. The presentations will explore the infrastructure required to process and store data generated by PAT and how the needs of Industry 4.0 can be met.

Global Pharmaceutical Production
In the pharmaceutical industry, both branded and generic drug manufacturers could improve speed to market by adopting a continuous process development and manufacturing approach. Process Analytical Technology (PAT) allows pharmaceutical producers to evolve from a batch production process to a continuous one. It therefore represents a key enabling technology that can lead to a better supply of affordable, safe and quality assured medicines worldwide.

IFPAC Cortona 2018
One of the key topics at the IFPAC Cortona Conference 2018 will be "Manufacturing Innovation and Global Regulatory Harmonization". In relation to this subject, Optimal Industrial Technologies will discuss how to address regulatory compliance and cyber security issues when implementing process analytical technologies (PAT) in pharmaceutical manufacturing processes. During the talk, Optimal will also discuss how PAT knowledge management platforms such as synTQ provide powerful and reliable software tools to provide quality assurance, data tracking and traceability.

IMA Symposium
The VIAVI Solutions and IMA Active symposium: "PAT and QbD in the solid dosage manufacturing: NIR integration from an engineering perspective" will run from 23-24 October 2018 at the IMA factory in Bologna, Italy.

Biomanufacturing Strategy Meeting Europe 2018
At Proventa International’s Biomanufacturing Strategy Meeting Europe 2018, Optimal Industrial Technologies will present how process analytical technology (PAT) knowledge management platforms such as synTQ, are benefitting biopharmaceutical processes worldwide. Controlling quality in real-time is reducing costs, delivering high-quality products and enabling the shift towards continuous manufacture.

Can Process Analytical Technology be rolled out?
Starting something new can be daunting, especially if it is big, complicated and important. Process Analytical Technology (PAT) is big and complicated and important; in fact, it looks like it will soon be indispensible for pharmaceutical production.

Is PAT the paradigm-shift that process manufacturing has been looking for?

Manufacturers worldwide are taking a closer look at how they can deliver cost-optimised, high-quality products.



Optimal hires new business development manager
With the popularity of process analytical technology (PAT) accelerating Optimal Industrial Technologies, a global leader in PAT knowledge management software, has appointed Ryan Dougall as business development manager to support the company's growth.

Interphex Japan 2018
At Interphex Japan 2018, Optimal’s regional Application Partner - Quality Design Co Ltd., will demonstrate the material benefits and latest updates for the market leading pharmaceutical production and development platform synTQ.